ZOLADEX

Mfd. by :- AstraZeneca (Fulfilled By : Magicine Pharma)

ZOLADEX

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name:- Zoladex 

Generic Name:- Goserelin Acetate 

Manufacturer:- AstraZeneca 

Strength:- 3.6mg 

Dosage:- Injection 

Indications:- Prostate Cancer, Breast Cancer, Endometriosis, and Uterine Fibroids 

Storage:- Store in a refrigerator. 

Overview  

Zoladex injection is a prescription medicine. It is an anticancer regimen used in the treatment of Prostate Cancer in men and Breast Cancer, Endometriosis, and Uterine Fibroids in women. This medicine is a synthetic hormone. Zoladex belongs to luteinizing hormone-releasing hormone (LHRH) agonists. It is used both in men and women, but for separate purposes. It is not safe for use in pregnant females.  

Pharmacodynamic

The active ingredient of Zoladex is Goserelin. This compound is a synthetic decapeptide analog of LHRH. It tends to act as a potent inhibitor of pituitary gonadotropin secretion when given in the biodegradable formulation. The result of the same is sustained suppression of LH and serum testosterone levels. The pharmacology of Goserelin has been determined in (both men and women) healthy individuals and patients. In such studies, the compound was given as a single 250µg (aqueous solution) dose and as a single or multiple 3.6 mg depot dose by subcutaneous route of administration. 

Usage of Zoladex  

Zoladex is prescribed for the treatment of certain types of cancers including cancer in the prostate gland, breast. In women, it is also used to treat Endometriosis and Uterine Fibroids. This medication is available in the form of an injection in the strength of 3.6mg. Zoladex (Goserelin Acetate) injection will be given under the skin by your healthcare professional. Do not self-administer.  

Interactions  

Some medicines, compounds, or diseases may interact with Zoladex (Goserelin Acetate) and cause severe reactions. Here’s a brief:- 

Alcohol  

Interaction of alcohol with Zoladex (Goserelin Acetate) injection is not known. Please consult a qualified medical practitioner. 

Diseases  

No disease interaction data is available by now. Please consult a qualified medical practitioner.  

Medicines 

  • Ivabradine  

  • Amiodarone 

  • Dolasetron 

  • Efavirenz 

  • Clozapine 

Contraindications 

  •  Hypersensitivity  

  • Zoladex (Goserelin Acetate) injection is not indicated for use in patients suffering from hypersensitivity.  

  • Allergy  

  • Zoladex injection is not safe for use in patients having an allergy to Goserelin Acetate.  

Side Effects  

Zoladex (Goserelin Acetate) injection may cause various side effects during treatment with this drug. The following are the common and serious reactions caused by this injection.  

Common Side Effects  

  • Hypersensitivity 

  • Anxiety 

  • Depression  

  • Irregular heartbeat 

  • Breast pain 

  • Tenderness  

  • Increase in blood glucose level  

  • Unusual sweating  

  • Hair growth  

  • Burning sensation in the vagina 

  • Pain during sex in women 

Serious Side Effects 

  • Severe bone pain  

  • Increase in blood sugar level 

  • Sudden vision changes  

  • Chest pain 

  • Heart attack  

  • Back pain 

  • Blood in urine  

  • Painful urination  

  • Swelling of the face or tongue 

Dosage  

Normal Dose  

Zoladex (Goserelin Acetate) injection will be given by your healthcare professional. Do not self-administer.  

Missed Dose 

In case of a missed dose, consult your healthcare professional for further guidance.  

Overdose 

Contact a medical emergency helpline or your healthcare provider immediately.  

Warnings and Precautions  

General Warnings  

  • Zoladex (Goserelin Acetate) injection may cause an increase in the blood sugar level of the patient.  

  • Regular monitoring of the blood sugar and blood pressure should be done.  

  • Inform your healthcare provider about the side effects you experience.  

  • Do not self-administer this injection.  

Warnings for Females  

Pregnancy  

  • In pregnant women, Zoladex (Goserelin Acetate) is not recommended for use because this medicine may cause fetal harm to the baby.  

Breastfeeding  

  • In nursing women, Zoladex (Goserelin Acetate) is not recommended for use because this medicine may cause fetal harm to the baby. 

Special Precautions 

Alcohol  

  • Drinking alcohol during the course of Zoladex (Goserelin Acetate) may cause adverse reactions.  

Driving  

  • It may not be safe to drive after taking Zoladex (Goserelin Acetate) because this drug may lead to side effects including dizziness and blurred vision. 

Kidney disease  

  • If you are having kidney disease, be sure to consult a medical professional to know the risks and benefits of administering Zoladex (Goserelin Acetate). 

Q1. What is Zoladex (Goserelin Acetate)? 

Ans. Zoladex injection is a prescription medicine. It is an anticancer regimen used in the treatment of Prostate Cancer in men and Breast Cancer, Endometriosis, and Uterine Fibroids in women.  

Q2. What are the side effects of Zoladex (Goserelin Acetate)? 

Ans. The side effects of Zoladex (Goserelin Acetate) injection are back pain, skin rash, chest pain, weakness, dizziness, sleepiness, shortness of breath, etc.  

Q3. What is the strength of Zoladex (Goserelin Acetate)? 

Ans. Zoladex (Goserelin Acetate) injection is available in the strength of 3.6mg. 

Q4. How can I take Zoladex (Goserelin Acetate)? 

Ans. Zoladex (Goserelin Acetate) injection will be given by your healthcare professional. Do not self-administer.   

Q5. Can I take Zoladex (Goserelin Acetate) during pregnancy? 

Ans. In pregnant women, Zoladex (Goserelin Acetate) injection is not recommended for use because this medicine may cause fetal harm to the baby 

Q6. Can I take Zoladex (Goserelin Acetate) during breastfeeding? 

Ans. In nursing women, Zoladex (Goserelin Acetate) is not recommended for use because this medicine may cause fetal harm to the baby.  

Q7. Is it safe to drive after taking Zoladex (Goserelin Acetate)? 

Ans. It may not be safe to drive after taking Zoladex (Goserelin Acetate) because this drug may lead to side effects including dizziness and blurred vision. 

Q8. Is it safe to drink alcohol during the course of Zoladex (Goserelin Acetate)? 

Ans. Drinking alcohol during the course of Zoladex (Goserelin Acetate) may cause adverse reactions. 

Q9. Can I take Zoladex (Goserelin Acetate) if I have kidney disease? 

Ans. If you are having kidney disease, be sure to consult a medical professioQ10. What happens if I miss a dose of Zoladex (Goserelin Acetate)? 

Ans. In case of a missed dose, consult your healthcare professional for further guidance. 

Above Content has been reviewed by Professionals