SORAFINA

Mfd. by :- Arechar Healthcare (Fulfilled By : Magicine Pharma)

Sorafina

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name - Sorafina

Generic Name - Sorafenib 

Manufacturer - Arechar Healthcare 

Dosage Form - Tablet (Oral Administration)

Strength - 200mg 

Composition - Sorafenib 

Packaging - 120 tablet (120 / bottle) 

Indication - Kidney cancer, Liver cancer, and Thyroid cancer

Storage - Store at room temperature 

Overview

Sorafina (Sorafenib) is used to treat certain types of cancer including liver cancer, kidney cancer, and thyroid cancer. It belongs to a group of medications called tyrosine kinase inhibitors. Sorafina (Sorafenib) helps to stop the growth of cancerous cells. It is available as a tablet, indicated for oral use. Do not take Sorafina (Sorafenib) tablet in the wrong way as it may lead to some severe side effects. Make sure not to change or skip the dose without consulting your doctor. Your healthcare provider will decide the exact dose and duration of Sorafina (Sorafenib) tablet. 

Pharmacodynamics of Sorafina (Sorafenib)

Sorafina is a kinase inhibitor that decreases tumor cell proliferation in vitro. Sorafina works to inhibit tumor growth of HCC, RCC, and DTC human tumor xenografts in immunocompromised mice. Reductions in tumor angiogenesis were seen in models of HCC and RCC upon Sorafina treatment, and increases in tumor apoptosis were observed in models of HCC, RCC, and DTC. 

Interactions

Interactions are more likely to change how your medicine works. Make sure to disclose your previous medical history with the healthcare professional. 

Medicine interaction 

  • Amiodarone

  • Clozapine 

  • Gatifloxacin 

  • Lomitapide 

  • Ziprasidone 

  • Moxifloxacin 

  • Bepridil 

Disease interaction  

  • Sorafina (Sorafenib) should be used cautiously in patients having a history of interstitial pneumonitis. 

Alcohol interaction 

  • Interaction with alcohol is unknown. Make sure to consult your healthcare professional before consuming alcohol. 

    Contraindications

  • Sorafina tablets are not indicated for use in patients having a known allergy to Sorafenib.  

  • Sorafina (Sorafenib) tablet is not recommended for use in patients with squamous cell cancer. 

Alternate Brands

 

Side effects of Sorafina (Sorafenib)

Sorafina (Sorafenib) tablets may cause some side effects. Make sure to consult your healthcare professional for the same. 

Common side effects 

  • Indigestion 

  • Hair loss 

  • Numbness 

  • Weight loss 

  • Dizziness 

  • Diarrhea 

  • Abdominal pain 

  • Fatigue

  • Anemia 

  • Fainting 

  • Lightheadedness 

  • Muscle cramps 

  • Anxiety 

  • Itching 

  • Vomiting 

  • Tiredness 

  • Difficulty in swallowing 

  • Coughing up blood 

  • Bleeding gums 

  • Nausea 

  • Bloating 

  • Difficulty in breathing 

  • Irregular heartbeat

  • Pale skin 

  • Seizures 

  • Sore throat

  • Rash 

  • Joint pain 

  • Dry mouth

  • Dehydration

  • Weakness 

  • Chest  pain 

  • Chills  

Dosage

Take Sorafina (Sorafenib) tablets as prescribed by your healthcare provider. Do not try to chew, break or crush the tablet. Take it on an empty stomach. 

Missed dose 

  •  It is advised not to miss a dose. If you skip a scheduled dose of Sorafina tablet, make sure to contact your healthcare provider immediately. 

Overdose 

  • In case you feel the symptoms of overdose, reach out to a doctor for help. 

Usage of Sorafina (Sorafenib)

Sorafina tablets work by slowing down the growth of cancer cells. Take this medicine orally on an empty stomach once a day. Try not to miss your regular dosing schedule. Take Sorafina exactly as prescribed by your doctor. Do not crush or chew the tablet. The dose and duration are decided by a medical advisor according to your medical condition and requirements.

Regular monitoring of BP is necessary while consuming this tablet. It is advised to keep yourself hydrated and maintain a healthy diet while consuming Sorafina tablet.

 

Warnings 

Before starting treatment with Sorafina tablet, please inform your doctor about your previous medical history. If you experience any symptoms while receiving Sorafina (Sorafenib), do not ignore those symptoms because it may lead to higher risk. 

 

  •  Contraception 

    • Use effective methods of contraception to prevent pregnancy while taking Sorafina tablet. 

  • Children and adolescents 

    • Sorafina tablet is not advisable for use in children and adolescents. 

Warnings for female 

  • Pregnancy 

    • Sorafina (Sorafenib) shouldn’t be used by pregnant women. Sorafenib may cause harm to the baby. It is recommended that this medicine should be avoided during pregnancy. 

 

  • Breastfeeding 

  • Sorafina (Sorafenib) is not recommended in breastfeeding unless it is required. Please consult your medical advisor before starting treatment.

Precautions

  • Regular monitoring of blood pressure is required during treatment with this medication. 

  • Sorafina (Sorafenib) medicine may increase the risk of bleeding. 

  • If you have low blood glucose levels do not take Sorafina tablet without consulting from your healthcare provider. 

  • Do not take Sorafina tablet, if you have a history of heart disease. 

  • Sorafina may cause dizziness in some patients. 

  • The use of Sorafina tablet may cause skin reactions.  

  • Sorafina medicine can reduce the number of white blood cells in the body. 

Cautions

  • Do not drive or operate heavy machinery. 

  • Do not break or chew the tablet. 

  • Not safe for pregnant women. 

  • Do not breastfeed while receiving this medication. 

Q1. What is Sorafina (Sorafenib)? 

Ans. This medication is used to treat a certain type of cancer (liver cancer, kidney cancer, and thyroid cancer) and it also helps to stop the growth of cancerous cells. Sorafina tablet belongs to a class of medication known as a tyrosine kinase inhibitor. 

 

Q2. How does Sorafina (Sorafenib) work? 

Ans. This medication works by blocking the action of a protein that signals the cancer cells to multiply. Sorafina (Sorafenib) helps in slowing down the growth of cancer cells.

 

Q3. In what strength is it available? 

Ans. Sorafina (Sorafenib) is available in the strength of 200mg. 

 

Q4. What are the side effects? 

Ans. Some common side effects of Sorafina (Sorafenib) are:- nausea, irregular heartbeat, seizures, pale skin, abdominal pain, bleeding, diarrhea, fatigue, etc. 

 

Q5. What are self-care tips? 

Ans. Maintain good nutrition and keep yourself hydrated. 

 

Q6. What happens if I miss a dose? 

Ans. If you miss a scheduled dose of Sorafina tablet, contact your doctor immediately. 

 

Q7. Can I consume alcohol while taking Sorafina tablet? 

Ans. Please consult your healthcare provider before consuming alcohol. 

 

Q8. What should I avoid while receiving Sorafina tablet? 

Ans. Follow your healthcare provider instructions about any restrictions on food and other activities.

 

Q9. Does this medicine affect liver function? 

Ans. Please contact your healthcare provider before consuming this drug. 

 

Q10. Can I take Sorafina (Sorafenib) during pregnancy?

Ans. Sorafina tablet is not recommended for pregnant women.

 

Q11. Can I drive after taking this medication? 

Ans. Sorafina (Sorafenib) may decrease your ability to drive or affect your vision. Do not drive if any symptoms occur. 

 

Q12. Can I take this medicine during breastfeeding? 

Ans. Sorafina (Sorafenib) is not recommended in breastfeeding unless it is necessary.

 

Q13. How to take this medicine? 

Ans. Take Sorafina (Sorafenib) on an empty stomach orally once a day. 

 

Q14. What are the storage conditions? 

Ans. Store Sorafina (Sorafenib) at room temperature. 

 

Above Content has been reviewed by Professionals