DACIHEP

Mfd. by :- zydus (Fulfilled By : Magicine Pharma)

dacihep

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Brand Name: Dacihep

Generic Name: Daclatasvir

Manufacturer: Zydus

Dosage Form: Tablet

Strength: 60mg

Composition: Daclatasvir

Packaging: 28 tablets per bottle

Indication: Hepatitis C

Storage: Store at room temperature

Overview

Dacihep (Daclatasvir) tablet is an antiviral medication used for the treatment of chronic (when

the infection moves into the long-lasting stage) Hepatitis C virus (HCV). This medication

reduces the amount of Hepatitis C virus in the body and helps our immune system to fight

against infection. It is also used along with other medications for the treatment. If you

experience any symptoms while receiving this medicine, inform your doctor immediately. It is

advisable not to change or stop the dose without taking suggestions from your doctor. Do not

take this medicine in the wrong way as it may lead to some severe side effects.

Pharmacodynamics

Daclatasvir is a direct-acting antiviral (DAA) agent that targets the nonstructural protein 5A

(NS5A) and causes a decrease in serum HCV RNA levels. It disrupts HCV replication by

specifically inhibiting the critical functions of a nonstructural protein 5A (NS5A) protein in the

replication complex. After the oral administration, the effect of this medicine can be observed in

2 hours.

Interactions

Interactions may change how your medication works and increase the risk for side effects. Don’t

forget to disclose your previous medical history with the doctor.

Medicine Interactions

● Carbamazepine

● Efavirenz

● Primidone

● Ketoconazole

● Atorvastatin

● Bosentan

● Dabigatran

● Clarithromycin

Disease Interaction

● In patients coinfected with hepatitis B and hepatitis C virus, the use of this medicine may

cause a reactivation of HBV.

Alcohol Interaction

● Interaction with alcohol is unknown. Please consult your doctor before consuming

alcohol.

Contraindications

● This medicine is not recommended in patients receiving strong CYP3A inducers.

● Do not take this medicine if you are allergic to Daclatasvir.

● This medicine is not recommended in patients known to be hypersensitive.

Side effects

This medicine may cause some mild or severe side effects. Discuss the risks and benefits of

this medication with the doctor before starting the treatment.

Common side effects

● Nausea

● Headache

● Fatigue

● Anemia

● Vomiting

● Diarrhea

● Shortness of breath

● Irregular heartbeat

● Chest pain

● Memory problems

● Severe rashes

● Fainting

● Unusual weakness

● Lack of strength

● Swelling of the mouth, face, tongue, or throat

● Unusual tiredness

● Slow heart rate

● Hepatitis B viral infection

● Low blood sugar

● Allergic reaction

● Abdominal cramps

● Sleep disturbances

● Dizziness

● Unusual tiredness

Note - Immediately contact your doctor if any side effects occur

Dosage

Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing

schedule.

Missed dose

● It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact

your doctor immediately.

Overdose

● In case of an overdose, the doctor will provide emergency medical treatment.

Usage

Dacihep tablet is used along with other medications for the treatment of Chronic Hepatitis C.

This medication works by lowering the load of the virus and removing Hepatitis C infection from

the blood over a period of time. Regular monitoring of liver function and the amount of Hepatitis

C infection in your body is required. Take this medicine with or without food orally once a day.

The recommended dose is decided by a doctor according to your previous medical condition

and response to the treatment. This medication may take some time to show effect. Do not

chew or break the tablet and swallow the whole tablet with a glass of water.

Warnings

Before starting treatment with this medication, please inform your doctor about your previous

medical history. If you experience any symptoms while receiving this medication, do not ignore

those symptoms because it may lead to higher risk.

● Contraception

○ Use suitable methods of contraception to prevent pregnancy while taking this

medicine.

● Children and adolescents

○ Dacihep tablets are not advisable for use in children and adolescents.

Warnings for female

● Pregnancy

○ Do not use this medicine if you are planning to become pregnant. Avoid this

medication at the time of pregnancy.

● Breastfeeding

○ This medicine is not recommended in breastfeeding unless it is essential. Please

consult with your doctor before starting treatment with this medication.

Precautions

● Inform your doctor if you experience any side effects like - nausea, anemia, fatigue,

vomiting, insomnia, and irregular heartbeat.

● One should test blood glucose levels more frequently while you are taking this

medication.

● Close monitoring of kidney and liver function tests is required while having treatment

with this medicine.

● This tablet may interact with many other medicines. Do not forget to discuss your

medical history with the doctor.

● Do not stop taking this medicine without your doctor’s advice.

Cautions

● Not safe for pregnant women.

● Do not breastfeed while receiving this medication.

● Do not skip the regular dosing schedule.

● Do not crush or break the tablet.

● Do not drive or operate heavy machinery.

Substitutes

● Daclafab

● Daclacure

● Mydekla

● Hepcfix

Q1. What is Dacihep (Daclatasvir)?

Ans. Dacihep (Daclatasvir) tablet is an antiviral medication used for the treatment of chronic

(when the infection moves into the long-lasting stage) Hepatitis C virus (HCV).

Q2. How to take this medicine?

Ans. Take this medicine as prescribed by your doctor.

Q3. What are the side effects?

Ans. Some common side effects are:- anemia, irregular heartbeat, insomnia, shortness of

breath, lack of strength, dizziness, etc.

Q4. How does Dacihep (Daclatasvir) work?

Ans. This medication reduces the amount of Hepatitis C virus in the body and helps our immune

system to fight against infection.

Q5. In what strength is it available?

Ans. It is available in the strength of 60mg.

Q6. What happens if I miss a dose?

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately.

Q7. What should I avoid while receiving this medication?

Ans. Follow your doctor’s instructions about any restrictions on food and other activities.

Q8. Can I consume alcohol while receiving this medicine?

Ans. Please consult your doctor before consuming alcohol.

Q9. Can I take this medicine during breastfeeding?

Ans. This medicine is not recommended in breastfeeding unless it is necessary.

Q10. Does this medicine affect liver function?

Ans. Please contact your doctor before consuming this drug.

Q11. Can I take this medicine during pregnancy?

Ans. This medicine is not recommended for pregnant women.

Q12. Does this medicine affect kidney function?

Ans. Please contact your doctor before consuming this drug.

Q13. Can I drive after taking this medicine?

Ans. This medicine may affect your vision. Do not drive if any symptoms occur.

Q14. What are the storage conditions?

Ans. Store this medicine at room temperature.

Above Content has been reviewed by Professionals