EXEMPTIA

Mfd. by :- Zydus Cadila (Fulfilled By : Magicine Pharma)

Exemptia

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Brand name: Exemptia

Generic name: Adalimumab

Strength: 40mg/0.8ml

Manufacturer: Zydus Cadila

Dosage form: Injection

Indication: Rheumatoid arthritis

Storage: Store in a refrigerator

Overview

Exemptia (Adalimumab) is available in the form of injection and the strength of 40mg/0.8ml. This injection is used for the treatment of various conditions (rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease, ulcerative colitis). Exemptia injection works by blocking the action of chemical messengers, which are responsible for certain joint diseases. Before starting treatment, inform your physician if you have a history of heart, liver, and kidney disease. Do not self-administer Exemptia medication. 

Pharmacodynamics

Adalimumab decreases the levels of acute-phase reactant proteins of inflammation (C­ reactive protein [CRP] and erythrocyte sedimentation rate [ESR]) and serum cytokines (IL-6) and it was compared to baseline in patients diagnosed with rheumatoid arthritis. In patients diagnosed with Crohn’s disease, a decreased level of CRP was also observed in them. Serum levels of matrix metalloproteinases (MMP-1 and MMP-3) that lead to the tissue remodeling responsible for cartilage destruction were also found to be decreased after administrating adalimumab in patients, reduction in signs and symptoms of disease, the induction of clinical response, and inhibition of structural damage, and improvements in physical function in adult and pediatric patients with various inflammatory conditions have been demonstrated. 

Usage

Exemptia (Adalimumab) injection belongs to a class of medications known as biological response modifiers. This injection helps in relieving symptoms like swelling, pain, and redness which are caused by various disorders (rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis, uveitis, chronic plaque psoriasis, etc.). The use of Exemptia medication may result in the formation of autoantibodies in some patients, immediate discontinuation of treatment is recommended on such patients. 

Interactions 

Use of Exemptia (Adalimumab) injection may interact with other medications and it can cause some unusual side effects. Do not forget to discuss it with your healthcare provider. 

Medicine Interactions

·         Budesonide

·         Azathioprine

·         Cisplatin

·         Betamethasone

·         Clozapine

·         Linezolid

·         Tacrolimus

·         Hydrocortisone

·         Cyclosporine

·         Triamcinolone

·         Altretamine

Disease Interactions

·         Malignancies

·         Congestive heart failure

·         Neurological disorders

·         Hepatitis B

·         Infections

·         Tuberculosis

 

Alcohol Interactions

·         Avoid consuming alcohol while receiving treatment with Exemptia (Adalimumab) 40mg/0.8ml injection because it may cause some side effects like dizziness. 

Contraindications

·         Use of Exemptia injection is not recommended in patients who are allergic to Adalimumab r any other inactive ingredients. 

·         Do not use Exemptia (Adalimumab) injection if you have a pre-existing problem of hypersensitivity. 

Alternate medicine
Olumiant

Following are the possible side effects that can occur during your treatment with Exemptia (Adalimumab) injection. Contact your healthcare provider if they last longer. 


 

  • Nausea 
  • Injection site reactions
  • Headache
  • Back pain
  • Vomiting
  • Numbness 
  • Burning sensation
  • Vision disturbances
  • Weakness 
  • Chest pain
  • Shortness of breath
  • Tingling in the arms and feet
  • Difficulty in swallowing
  • Skin rash
  • Chills 
  • Swelling
  • Blurred vision 
  • Muscle pain 
  • Irregular heartbeat 
  • Bruising 
  • Itching 
  • Joint pain
  • Fever 
  • Unusual bleeding
  • Pale skin
  • Red patches on the skin
  • Heartburn 
  • Ear congestion
  • Black or tarry stools
  • Sleep disturbances
  • Upper respiratory tract infection
  • Difficulty in breathing 

 

Note - contact your medical practitioner immediately if any of the above-mentioned side effects occur.

Exemptia (Adalimumab) injection is administered by a qualified nurse or medical professional and recommended dosage is decided by your physician according to your medical history and current health conditions. 

Missed Dose

If you miss a scheduled dose of Exemptia (Adalimumab) contact your health professional as soon as possible. Try not to miss or skip your dosage of Exemptia injection. 

Overdose 

In case of an overdose of Exemptia (Adalimumab), contact your medical practitioner immediately in order to avoid severe side effects. 

Before starting treatment with Exemptia (Adalimumab) injection, check all the possible risks and benefits with your healthcare provider. Use of Exemptia injection may cause severe allergic reactions in some patients. 

Warnings for females 

·         Pregnancy 

o    Exemptia (Adalimumab) injection is not recommended for use in pregnant women because it may affect the unborn baby. 

·         Breastfeeding

o    Do not use Exemptia (Adalimumab) injection in breastfeeding. Talk to your healthcare provider before starting treatment with Exemptia. 

Precautions 

·         Use of Exemptia (Adalimumab) injection may affect your immune system, avoid contact with people who have infections.

·         Caution is recommended in patients who have pre-existing nervous system disorders like multiple sclerosis and optic neuritis.

·         Close monitoring of hematological function is required during treatment with Exemptia injection. 

·         Discontinue the use of Exemptia (Adalimumab) if severe allergic reactions occur. 

·         Exemptia injection may increase the risk of reactivation of hepatitis b virus in some patients 

·         Exemptia medication may result in the formation of autoantibodies in some patients, immediate discontinuation of treatment is recommended in such conditions.

Cautions 

·         Do not self-administer Exemptia (Adalimumab)

·         Do not drive or operate heavy machinery 

·         Do not skip a dose

·         Do not overdose 

Q1. What is Exemptia (Adalimumab)?

Ans. Exemptia injection is used for the treatment of various conditions (rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease, ulcerative colitis).

 

Q2. How to use Exemptia (Adalimumab)?

Ans. Use Exemptia injection as prescribed by your healthcare provider and it is administered by a qualified nurse. 

 

Q3. Does Exemptia (Adalimumab) cause any side effects?

Ans. Some common side effects are - nausea, weakness, pale skin, irregular heartbeat, difficulty in breathing, vomiting, fever, etc. 

 

Q4. What happens if I overdose Exemptia (Adalimumab)?

Ans. It is advisable to consult your medical practitioner in case of an overdose of Exemptia injection. 

 

Q5. Is it safe to use Exemptia (Adalimumab) during pregnancy?

Ans. Use of Exemptia injection is not recommended for use in pregnancy. 

 

Q6. Does Exemptia (Adalimumab) affect kidney function?

Ans. Consult your health professional and discuss the risk and benefits of Exemptia injection.

 

Q7. Can I drive after taking Exemptia (Adalimumab)?

Ans. It is not advisable to drive after taking Exemptia because it can cause side effects like blurred vision and dizziness. 

 

Q8. In what strength is Exemptia (Adalimumab) available?

Ans. Exemptia injection is available in the strength of 40mg/0.8ml

 

Q9. Can I consume alcohol while receiving Exemptia (Adalimumab)?

Ans. Consult it with your medical practitioner, before starting treatment with Exemptia injection.

 

Q10. What are the storage conditions Exemptia (Adalimumab)?

Ans. Store Exemptia injection in the refrigerator. 

Above Content has been reviewed by Professionals