POSID

Mfd. by :- Cadila (Fulfilled By : Magicine Pharma)

Posid

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name:- Posid 

Generic Name:- Etoposide 

Manufacturer:- Cadila 

Dosage Form:- Injection 

Strength:- 100mg/5ml 

Composition:- Etoposide 

Packaging:- 1 vial 

Indication:- Ovarian cancer, Leukemia, Lymphoma, Testicular cancer, and Prostate cancer. 

Storage:-  Store at room temperature. 

Overview

Posid (Etoposide) is used to treat certain types of cancer (small cell lung cancer, acute leukemia, bladder cancer, cancer of testicles). It works by suppressing the activity of an enzyme involved in DNA. It helps to stop the growth of cancer cells. It is given as an infusion into the vein. Do not self administer this medicine. Take this medicine as prescribed by your medical advisor. Your doctor will decide the exact dosage. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change or stop the dose without taking suggestions from your doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately.  

Pharmacodynamics of Posid (Etoposide)

Etoposide inhibits DNA topoisomerase II, thereby inhibiting DNA re-ligation. This causes critical errors in DNA synthesis at the pre mitotic state of cell division and can lead to apoptosis of the cancer cell. 

Substitutes of Posid (Etoposide)  

  • Etoglan  

  • Topside  

  • Oncosid  

  • Etoglan  

  • Fytosid 

Side effects of Posid (Etoposide)

This medicine may cause some unwanted side effects. It requires immediate medical attention otherwise it can also lead to higher risk. Discuss the risks and benefits of this medication with the doctor before starting the treatment. 

Common side effects 

  • Anemia 

  • Diarrhea 

  • Low blood pressure 

  • Nausea 

  • Infections 

  • Rash 

  • Heart attack 

  • Vomiting 

  • Stomatitis 

  • Decreased blood cells 

  • Liver damage 

  • Hair loss 

  • Seizures 

  • Decreased white blood cells

  • Painful swallowing 

  • Dizziness 

  • Abdominal pain 

  • Constipation 

  • Bleeding 

  • Mouth sore 

  • Weakness 

  • Difficulty in breathing 

  • Irregular heartbeat 

  • Allergic reaction 

  • Loss of appetite 

  • Pale skin 

  • Weight loss 

  • Skin pigmentation 

  • Fever 

  • Back pain 

  • Cough 

  • Blood in urine 

Note- Immediate medical attention is required if any side effect occurs.

Dosage

Take this injection as prescribed by your doctor. Do not self administer.  The injection is given as an infusion into your vein by a doctor or nurse. 

Missed dose 

  •  It is advisable not to miss a dose. If you miss an appointment for a scheduled dose of this medicine, contact your doctor immediately. 

Overdose 

  • In case of an overdose, the doctor will provide emergency medical treatment. 

Usage of Posid (Etoposide)

This medicine is used to treat different cancers of the lungs and testicles. This injection is also used to treat cancer that affects ovaries and a certain type of white blood cells. Take this medicine according to your dosing schedule. This medicine must be given slowly as an infusion into the vein.  The dose of medicine is decided by a medical advisor according to your response to the treatment and your previous medical condition. This medicine is not recommended in pregnant women. Avoid activities that may increase the risk of bleeding. Do not shake or freeze the medicine. 

Warnings

Before starting treatment with Posid, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk. 

  •  Contraception 

    • Use effective methods of contraception while taking this medicine. 

  • Children and adolescents 

    • This medicine is not advisable for use in children and adolescents. 

General warning and precaution  

  • This medicine may cause drowsiness.  

  • Posid injection may increase the risk of breathing difficulties, low blood pressure, fever, etc.  

  • Close monitoring of blood cell count is required during treatment with this medicine.  

  • This medicine is highly unsafe in children.  

  • This medicine may cause bone marrow suppression.  

  • Do not receive any vaccines while having treatment with this medicine. 

Cautions 

  • Do not drive or operate heavy machinery. 

  • Do not self-administer this medicine.

Q1. What is Posid (Etoposide)?

Ans. Posid (Etoposide) is used to treat certain types of cancer (small cell lung cancer, acute leukemia, bladder cancer, cancer of testicles). 

Q2. How does Posid (Etoposide) work? 

Ans. It is an anti-cancer medication. It works by suppressing the activity of an enzyme involved in DNA. It helps to stop the growth of cancer cells. 

Q3. What are the side effects? 

Ans. Some common side effects are:- nausea, abdominal pain, indigestion, low blood pressure, irregular heartbeat, anemia, vomiting, fever, etc. 

Q4. How is Posid given? 

Ans. This medicine must be given slowly as an infusion into the vein. 

Q5. In what strength is it available? 

Ans. It is available in the strength of 100mg/5ml. 

Q6. What happens if I miss a dose? 

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q7.  What should I avoid while receiving this medication? 

Ans. Follow your doctor’s instructions about any restrictions on food or physical activities. 

Q8. Can I drive after taking this medicine? 

Ans. This medicine may affect your vision. Do not drive if any symptoms occur. 

Q9.  Does this affect kidney function? 

Ans. Please consult your doctor, before consuming this drug. 

Q10. Can I consume alcohol while taking this medicine? 

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q11. Can I take this medicine during breastfeeding? 

Ans.  This medicine is not recommended in breastfeeding unless it is necessary.

Q12. Does this medicine affect liver function? 

Ans. The use of this medicine is not recommended in patients with liver disease.

Q13. Can I take this medicine during pregnancy?

Ans. This medicine is not recommended for pregnant women. 

Q14. What are the storage conditions? 

Ans. Store this medicine at room temperature. Do not freeze or shake the medicine.

Interactions

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor. 

Medicine interaction  

  • Carboplatin  

  • Phenobarbital  

  • Adalimumab  

  • Phenytoin  

  • Clozapine  

Disease interaction  

  • This medicine is not recommended in patients who have infections.  

  • This medicine should be used with extra caution in patients with myelosuppression.  

Alcohol interaction  

  • Interaction with alcohol is unknown. Please contact your doctor before consuming alcohol. 

Contraindication  

  • This medicine is not recommended in patients with severe bone marrow suppression. 

  • Posid injection is not recommended for use in patients with a known allergy to Etoposide.  

  • This medicine is contracted in patients known to be hypersensitive.

Above Content has been reviewed by Professionals