TS-ONE
Prescription Required
Manufactured By
taiho
Pack of
56 capsule
Salt Composition
Tegafur, Gimeracil, Oteracil Potassium
Storage
Keep in cold place
Delivering To:
Overview
TS-ONE Capsule is an anti-cancer medicine used in the treatment of Gastric Cancer with other medications like Cisplatin. It is also used in the treatment of head and neck cancer, lung, biliary tract, breast, pancreatic, and colorectal cancer. TS-ONE capsules comprise three agents namely tegafur (FT), gimeracil (CDHP), and oteracil potassium (Oxo).
Indication
Gastric Cancer
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Description
The antitumor activity of TS-ONE after its administration (orally) is based on 5-fluorouracil (5-FU) which tends to appear gradually in the body via the transformation of FT. CDHP increased the 5-FU’s concentration, which is converted from FT, by selectively and reversibly inhibiting DPD, a catabolic enzyme of 5-FU, which is particularly distributed in the liver. 5-fluoronucleotides, phosphorylated metabolites of 5-FU, are highly maintained in tumor tissues, thereby enhancing the antitumor activity in proportion to the increase in the concentration of 5-FU in the body. Oxo works to selectively inhibit the production of 5-fluoronucleotides from 5-FU by enabling the distribution in the gastrointestinal tissue as a result of the medicine’s administration and selectively inhibiting orotate phosphoribosyltransferase.
Side Effects
TS-ONE Capsules may cause certain side effects. Some of the common and serious side effects are stated below. Make sure to contact your healthcare professional if side effects occur after administration or last longer than usual.
Fever
Headache
Chills
Nausea
Sore throat
Malaise
Dehydration
Diarrhea
Abdominal pain
Speech disorder
Sensory disturbance
Tiredness
Lack of energy
Vomiting
Irregular heartbeat
Unusual bleeding
How To Use
The doctor will recommend the dose strength and frequency of your dose as per your health condition and the body’s tolerance. Take the capsule as a whole with water. Do not crush or cut it.
Safety Advice
Alcohol
unsafe
It is advisable not to consume alcohol while taking medicine.
Pregnancy
consult your doctor
Do not take TS-ONE Capsules without consulting the doctor, in case of pregnancy.
Breast Feeding
consult your doctor
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
caution
Do not take TS-ONE Capsules without a doctor's consultation in case of kidney problems.
Liver
caution
Share your medical history with the doctor in case of liver disease before taking this medicine.
Missed Doses
If you forget to take a dose of TS-ONE Capsules, consult your doctor. Don’t double up the next dose to cope with the missed one unless your doctor recommends it.
Quick Tips
FAQs
TS-ONE is used in the treatment of Gastric Cancer with other medications like Cisplatin. It is also used in the treatment of head and neck cancer, lung, biliary tract, breast, pancreatic, and colorectal cancer.
Store TS-ONE Capsules below 25°C. Keep this medicine away from children
Take the capsule as a whole with water. Do not crush or cut it.
Smoke (of any kind) should be avoided, in general. However, its interaction with this medication is not discovered yet. Consult your physician.
Some of the common side effects of TS-ONE capsules are fever, headache, nausea, vomiting, chills, shortness of breath, etc. Make sure to contact your healthcare professional if side effects occur after administration or last longer than usual.
