T-LAMIRENZ

Mfd. by :- Arechar Healthcare (Fulfilled By : Magicine Pharma)

T-Lamirenz

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: T-Lamirenz  

Generic Name: Lamivudine + Tenofovir disoproxil fumarate + Efavirenz 

Manufacturer: Arechar  

Dosage Form: Tablet  

Strength: 300mg/300mg/600mg 

Composition: Lamivudine (300mg) + Tenofovir disoproxil fumarate (300mg) + Efavirenz (600mg) 

Indication: HIV 

Packaging: 30 tablet  

Storage: Store at room temperature 

Overview  

Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz are active ingredients that are used in the treatment of HIV, and together they form a tablet known as T-Lamirenz and these ingredients work in a combination to prevent HIV infection. This tablet belongs to a class of medications known as NRTIs (nucleoside reverse transcriptase inhibitors). T-Lamirenz boosts your immune system to fight against the infection.  

Pharmacodynamics 

Lamivudine (T-Lamirenz):- It is a nucleoside reverse transcriptase inhibitor with activity against HIV Type 1 and Hepatitis B Virus in order to disrupt viral DNA synthesis. When phosphorylated, this compound can form active metabolites that compete for incorporation into viral DNA. Through this process, Lamivudine metabolites work to inhibit the activity of the HIV reverse transcriptase enzyme. They act as a chain terminator of DNA synthesis. 

Tenofovir Disoproxil Fumarate (T-Lamirenz):- This is particularly a nucleoside (acyclic) phosphonate diester analog of adenosine monophosphate. It usually requires initial diester hydrolysis in order to convert it to tenofovir and subsequent phosphorylations through cellular enzymes and form tenofovir diphosphate. It works to inhibit the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination.  

Efavirenz (T-Lamirenz):- It is an oral non-nucleoside reverse transcriptase inhibitor. This compound is a synthetic purine derivative. It is similar to zidovudine stavudine. It was originally approved to treat HIV infections and AIDS in patients who failed therapy with zidovudine.   

Usage  

T-Lamirenz (Lamivudine + Tenofovir disoproxil fumarate + Efavirenz) anti-HIV tablet is used to stop the growth of HIV (human immunodeficiency virus) infection. This medicine decreases the risk of catching more infections. It is advisable to take this medicine as prescribed by your medical practitioner and do not skip your regular dosing schedule. It is necessary to inform your doctor if you have a history of cardiac disease or liver disease. 

Interactions  

T-Lamirenz tablets may interact with other medicines, diseases, and other elements. It is important to know the same before starting the course of this medicine.  

Medicine Interactions  

  • Ciprofloxacin  

  • Methotrexate  

  • Aspirin  

  • Fluconazole 

  • Cisplatin  

  • Amiodarone 

  • Tobramycin  

Disease Interactions  

  • Hepatoxicity  

  • CNS disorders 

  • Renal dysfunction  

Alcohol Interaction 

T-Lamirenz may or may not interact with alcohol. Please consult a qualified doctor before consuming alcohol.  

Contraindication 

  • Do not administer T-Lamirenz tablets if you have an allergy to Lamivudine, Efavirenz, and Tenofovir Disoproxil Fumarate. 

  • T-Lamirenz tablets are not indicated for use in patients suffering from hypersensitivity.  

  • T-Lamirenz tablets are not recommended for use in patients suffering from kidney impairment. 

Side Effects 

T-Lamirenz (Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz) tablets may cause certain side effects. Make sure to inform a qualified healthcare professional about the same and know the ways to manage them.  

Common side effects  

  • Headache  

  • Tiredness  

  • Loss of weight 

  • Nausea 

  • Insomnia 

  • Diarrhea 

  • Blood in urine 

  • Irregular heartbeat 

  • Abnormal dream  

  • Fever  

  • Chills  

  • Loss of strength  

  • Fatigue  

  • Sore throat  

  • Unusual weakness  

  • Blurred vision  

  • Indigestion  

  • Constipation 

  • Redness of skin 

  • Abdominal pain  

  • Heartburn  

Note - consult your pharmacist or healthcare professional if any possible side effects occur. 

Dosage  

Take the T-Lamirenz tablets exactly as prescribed by a qualified doctor. Do not crush or chew the tablet. Be sure to avoid skipping a dose.  

Missed dose  

If you miss a dose, consult a qualified doctor. Do not increase the strength of the next dose to cope.  

Overdose 

In case of overdose, be sure to consult a healthcare professional or a medical helpline for proper monitoring.   

Warnings 

General warnings 

  • Do not administer T-Lamirenz tablets without a prescription. 

  • Tell your doctor about the medicines you take before consuming T-Lamirenz tablets.  

  • If you are suffering from liver or/and kidney disease, avoid the consumption of T-Lamirenz tablets, until your healthcare provider prescribes.  

Warnings for female  

Pregnancy  

  • During pregnancy, T-Lamirenz tablets may cause harm to the developing baby.  

Breastfeeding  

  • During breastfeeding, T-Lamirenz tablets may cause harm to the developing baby.  

Precautions 

  • Use proper contraceptive measures in order to avoid pregnancy during the course of this medicine.  

  • Know about the risks and benefits of taking T-Lamirenz tablets before their consumption.  

  • If side effects last longer than usual, inform your doctor about the same and know the ways to manage them.  

Cautions  

  • Do not crush the T-Lamirenz tablets.  

  • Avoid missing a dose.  

  • Do not increase or decrease the dose strength as per your own wish.  

  • Avoid smoking and alcohol consumption during treatment with this medicine.  

Q1. What is T-Lamirenz (Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz) tablets? 

Ans. T-Lamirenz (Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz) tablet is an antiviral medication that prevents the human immunodeficiency virus (HIV) from multiplying in your body.  

Q2. How do T-Lamirenz tablets work? 

Ans. T-Lamirenz (Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz) works to boost immunity in order to fight against HIV infection. It increases the CD4 cell count in the body. 
 

Q3. Can I drink alcohol while taking T-Lamirenz tablets?  

Ans. It is not known whether T-Lamirenz interacts with alcohol or not. Consult a qualified medical practitioner before consuming alcohol with this medicine.   
 

Q4. Can I take T-Lamirenz tablets in liver impairment? 

Ans. If you are suffering from a liver impairment, do not administer T-Lamirenz tablets without discussing their risks with your doctor.  
 

Q5. What happens if I miss a dose of T-Lamirenz tablets?  

Ans. If you miss a dose, be sure to contact your healthcare professional to get the needed guidance. Do not increase the strength of the dose to cope with the skipped dose.  

 

Q6.  What are the side effects of T-Lamirenz tablets? 

Ans. Some common side effects of T-Lamirenz tablets are fatigue, blurred vision, weight loss, sore throat, headache, nausea, taste change, stomach ache, peripheral neuropathy, and abnormal dreams. 

 

Q7. In what strength are T-Lamirenz tablets available?  

Ans. It is available in the strength of 300mg/300mg/600mg. 

 

Q8.  Can I drive after taking T-Lamirenz tablets?  

Ans. T-Lamirenz tablets may affect your vision. Do not drive if such symptoms occur.  
 

Q9. Can I take T-Lamirenz tablets during pregnancy?  

Ans. T-Lamirenz tablets are not indicated for use during pregnancy. 

 

Q10. What are the storage conditions for T-Lamirenz tablets? 

Ans. Store T-Lamirenz tablets at room temperature

Above Content has been reviewed by Professionals