PACLITERO

Mfd. by :- Hetero (Fulfilled By : Magicine Pharma)

Paclitero

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Brand Name:- Paclitero

Generic Name:- Paclitaxel 

Manufacturer:- Hetero 

Dosage Form:- Injection

Strength:- 100mg 

Composition:- Paclitaxel 

Packaging:- 1vial

Indication:- Breast, Pancreatic, Non-small cell lung cancer. 

Storage:- Store at room temperature. 

Overview 

Paclitero (Paclitaxel) is an anti-cancer medication which is used in the treatment of breast, pancreatic, and non-small cell lung cancer. This medication is given as an injection by your doctor or nurse. This injection works by stopping the growth of cancer cells in the body. Your doctor will decide your exact dosage. Take this medicine according to your doctor’s dosing schedule. Do not take this medicine in the wrong way as it may lead to some severe side effects. Close monitoring of blood cell count is required during treatment with this medicine. 

Pharmacodynamics of Paclitero (Paclitaxel)

Paclitero is a microtubule inhibitor that promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing depolymerization. Paclitero induces the bundles of microtubules throughout the cell cycle and multiple asters of microtubules during mitosis. It takes 30 and 180 minutes infusion of paclitero at a dose level of 80 to 375mg.

Substitutes of Paclitero (Paclitaxel)

  • Cytax 

  • Petaxel 

  • Taxol 

  • Mitotax 

  • Paxuba

Side effects of Paclitero (Paclitaxel)

This medicine may cause some serious and unwanted side effects. Which requires immediate medical attention otherwise it can also lead to higher risk. Do not forget to discuss the risk and benefits of this medication with your doctor. 

Common side effects 

  • Nausea 

  • Rash 

  • Bleeding 

  • Weakness 

  • Vomiting 

  • Low blood pressure 

  • Muscle pain 

  • Constipation 

  • Swelling 

  • Joint pain 

  • Hair loss 

  • Decreased white blood cell count 

  • Tingling and numbness of feet and hand 

  • Fatigue 

  • Low blood platelets 

  • Swelling and redness on the injection site 

  • Fungal infection 

  • Dizziness 

  • Difficulty in swallowing 

  • Sore mouth 

Serious side effect 

  • Difficulty in breathing 

  • Pale skin 

  • Allergic skin reactions 

  • Painful urination 

  • Neutropenia 

  • Fever and chills 

  • Difficulty in breathing 

  • Mouth ulcers 

  • Chest discomfort 

  • Diarrhea 

  • Chest discomfort 

  • Anemia 

  • Slower heartbeat 

Note- If any of these side effects occur, please contact your doctor

Dosage

Use this injection as prescribed by your doctor. Do not take this medicine in the wrong way and make sure to take this medication according to your dosing schedule. Dose administration should be decided by your doctor according to your response to the treatment. 

Missed dose 

  • In case you missed a dose, immediately contact your doctor. It is important to take the dose of this medicine as scheduled by your medical advisor. 

Overdose 

  • Emergency medical treatment is required. Please contact your medical advisor in case of an overdose.

Usage of Paclitero (Paclitaxel)

This medicine is used in the treatment of cancer that affects the female reproductive system, breast cancer, non-small cell lung cancer, and Kaposi’s sarcoma (a type of cancer that develops under the skin, mouth, or sore). Do not stop the use of this medicine without taking permission from your doctor. Try no to miss your dosing schedule. Usage of this medicine depends on your medical condition and your response to the treatment. 

Warning

Before starting treatment with Paclitero, do not forget to discuss your previous medical history with your doctor. 

  •  Contraception 

    • Use effective methods of contraception to prevent pregnancy while taking this medicine. 

  • Children and adolescents 

    • This medicine is not advisable for use in children and adolescents. 

Warnings for female 

  • Pregnancy 

    • Paclitero injection shouldn’t be used by women who are pregnant. It is recommended that this medication should be avoided during pregnancy. 

  • Breastfeeding 

    • This medicine is not recommended for use in breastfeeding women unless it is necessary. Please consult your doctor. 

General warnings and precautions

  • Close monitoring of blood cell count is required during treatment with this medicine. 

  • This medicine may cause some severe infections. 

  • This medication is not recommended in patients who are suffering from liver injuries. 

  • This medicine may cause serious skin allergies. 

Cautions

  • Do not drive or operate heavy machinery. 

  • May harm the liver. 

  • Not safe for pregnant women.

  • Decrease white blood cell count.

Q1. What is Paclitero (Paclitaxel)? 

Ans. This injection is an anti-cancer medication which is used in the treatment of breast cancer, pancreatic, and non-small cell lung cancer. 

Q2. How does this medication work? 

Ans. This medication works by interfering with the microtubule structures which help the cancer cells to divide. This slows the growth of cancer cells and destroys them. 

Q3. How to take this injection? 

Ans. This medication is given as an injection into your vein by your doctor or nurse. This infusion is given once every three weeks. 

Q4. What are the common side effects? 

Ans. Some common side effects are:- vomiting, shortness of breath, diarrhea, swelling, fever, sore mouth, low blood pressure, weakness, dizziness, etc. 

Q5. In what strength is it available? 

Ans. It is available in the strength of 100mg. 

Q6.How long does it take for this medicine to show effect?

Ans. The effect of this medicine can be observed in 1 hour. 

Q7. What if I miss a dose? 

Ans. In case you miss a dose, immediately contact your doctor. 

Q8. Can I drive after taking this medicine? 

Ans. Do not drive if you experience any symptoms of dizziness because it may affect your ability to drive. 

Q9. Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended for pregnant women. 

Q10. Can I take this medicine during breastfeeding? 

Ans. This medicine is not recommended for use in breastfeeding women unless it is necessary. 

Q11. Can I consume alcohol while taking this medicine? 

Ans. Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol. 

Q12. Where is the Paclitero injection approved? 

Ans. This injection is approved in the United States, India, and Japan.

Q13. What should I avoid while receiving this medicine? 

Ans.  Follow your doctor’s advice about any restrictions.

Q14. What are the storage conditions? 

Ans. Store this medicine at room temperature.

Interactions

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to discuss your previous medical history with your medical advisor. 

Medicine interaction 

  • Clozapine 

  • Atorvastatin 

  • Doxorubicin 

  • Cisplatin 

  • Diltiazem 

  • Trastuzumab

Disease interaction 

  • This medicine is known to cause cardiac conduction abnormalities. 

  • This medicine causes serious infection.

Alcohol interaction

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol. 

Contraindications

  • Paclitero injection is contraindicated in patients with known allergy to paclitaxel. 

  • Paclitero injection is contraindicated in patients with hypersensitivity. 

  • Not recommended in patients with neutrophils count 1,500cells/mm3.

Above Content has been reviewed by Professionals