
Bortero 2mg injection
Salt Composition: Bortezomib Injection IP
Expiry Date: 01/2028
Inclusive of all taxes
1 injection
About The Product
Blood cancer
Bortero is an anti-cancer medicine. Bortero injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. The active ingredient in Bortero is Bortezomib. Bortezomib is a dipeptide boronic acid derivative and a proteasome inhibitor. It is used in the treatment of multiple myeloma and mantle cell lymphoma. It is a reversible inhibitor of the 26S proteasome.
Description
Bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26S proteasome in mammalian cells. The 26S proteasome is a large protein complex that degrades ubiquitinated proteins.
The active site of the proteasome has chymotrypsin-like, trypsin-like, and post-glutamyl peptide hydrolysis activity. The 26S proteasome degrades various proteins critical to cancer cell survival, such as cyclins, tumor suppressors, BCL-2, and cyclin-dependent kinase inhibitors.
Inhibition of these degradations sensitizes cells to apoptosis. Bortezomib is a potent inhibitor of 26S proteasome, which sensitizes activity in dividing multiple myeloma and leukemic cells, thus inducing apoptosis.
In addition, bortezomib appears to increase the sensitivity of cancer cells to traditional anticancer agents (e.g., gemcitabine, cisplatin, paclitaxel, irinotecan, and radiation).
Side Effects
Most side effects of the Bortero injection do not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately.
Fatigue
Anemia (low number of red blood cells)
Nausea
Vomiting
Fever
Dizziness
Diarrhea
Constipation
Decreased appetite
Low blood platelets
Peripheral neuropathy (tingling and numbness of feet and hands)
Psychiatric disturbances
Neutrophils (decrease in white blood cell count)
How To Use
- Your healthcare provider will decide what dose is necessary for you, based on your existing medications.
- If you miss a dose, please get in touch with your healthcare provider.
Safety Advice
It is advisable not to consume alcohol while taking this medicine.
Do not take Bortero injection without consulting the doctor, in case of pregnancy.
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Do not take Bortero injection without a doctor's consultation in case of kidney problems.
Share your medical history with the doctor in case of liver disease before taking this medicine.
Missed Doses
- If you miss any dose, consult your doctor.
- Do not take twice the dose to catch up on the missed one.
- This will cause severe side effects and impact your overall health and duration of treatment.
FAQs
Bortero Injection is used in the treatment of multiple myeloma.
Medical Disclaimer
Accurate, reviewed information to support informed healthcare decisions
Magicine's primary objective is to ensure that its customers receive accurate, genuine, and trustworthy information reviewed by medical experts.
The content on this website has been produced solely for informational purposes. This is not intended to take the place of medical advice and care provided by a licensed professional, though.
This information may not include all potential side effects, warnings, and details about specific lab tests, medications, and medical conditions. Please ask your doctor any questions you may have about any drug or disease.
Our goal is not to replace or substitute for the doctor-patient relationship, but to uphold and strengthen it.
