Bortero 2mg injection

Bortero 2mg injection

Prescription requiredRx Required

Salt Composition: Bortezomib Injection IP

Expiry Date: 01/2028

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1 injection

About The Product

Blood cancer

Bortero is an anti-cancer medicine. Bortero injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. The active ingredient in Bortero is Bortezomib. Bortezomib is a dipeptide boronic acid derivative and a proteasome inhibitor. It is used in the treatment of multiple myeloma and mantle cell lymphoma. It is a reversible inhibitor of the 26S proteasome.

Description

​ Bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26S proteasome in mammalian cells. The 26S proteasome is a large protein complex that degrades ubiquitinated proteins.

The active site of the proteasome has chymotrypsin-like, trypsin-like, and post-glutamyl peptide hydrolysis activity. The 26S proteasome degrades various proteins critical to cancer cell survival, such as cyclins, tumor suppressors, BCL-2, and cyclin-dependent kinase inhibitors.

Inhibition of these degradations sensitizes cells to apoptosis. Bortezomib is a potent inhibitor of 26S proteasome, which sensitizes activity in dividing multiple myeloma and leukemic cells, thus inducing apoptosis.

In addition, bortezomib appears to increase the sensitivity of cancer cells to traditional anticancer agents (e.g., gemcitabine, cisplatin, paclitaxel, irinotecan, and radiation). ​

Side Effects

Most side effects of the Bortero injection do not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately.

Fatigue  

Anemia (low number of red blood cells) 

Nausea  

Vomiting 

Fever  

Dizziness  

Diarrhea  

Constipation  

Decreased appetite  

Low blood platelets 

Peripheral neuropathy (tingling and numbness of feet and hands) 

Psychiatric disturbances 

Neutrophils (decrease in white blood cell count)  

How To Use

  • ​ Your healthcare provider will decide what dose is necessary for you, based on your existing medications.
  • If you miss a dose, please get in touch with your healthcare provider. ​

Safety Advice

Alcohol

It is advisable not to consume alcohol while taking this medicine.

Pregnancy

Do not take Bortero injection without consulting the doctor, in case of pregnancy.

Breast Feeding

Without a doctor's consultation, do not take this medicine if you're breastfeeding.

Driving

It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.

Kidney

Do not take Bortero injection without a doctor's consultation in case of kidney problems.

Liver

Share your medical history with the doctor in case of liver disease before taking this medicine.

Missed Doses

  • If you miss any dose, consult your doctor.
  • Do not take twice the dose to catch up on the missed one.
  • This will cause severe side effects and impact your overall health and duration of treatment. ​

FAQs

​ Bortero Injection is used in the treatment of multiple myeloma.

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