BORTECINE

Mfd. by :- Arechar Healthcare (Fulfilled By : Magicine Pharma)

Bortecine

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name:- Bortecine
Generic Name:- Bortezomib
Manufacturer:- Arechar Healthcare
Strength:- 2 mg
Dosage:- Injection
Storage:- Store at room temperature (10-30°C)
Indication:- Multiple Myeloma and Mantle Cell Lymphoma
Prescription required:- Yes

Overview

Bortecine 2mg injection is an anti-cancer medication, prescribed for the treatment of Multiple Myeloma (a Cancer of Bone Marrow) and Mantle Cell Lymphoma. It is a prescription medicine comprising Bortezomib, an N-protected dipeptide. It is usually recommended for use in combination with other medications. Bortecine (Bortezomib) is given as an injection by the medical practitioner. This medicine works by slowing the multiplication of cancer cells in the human body. 

Usage of Medicine

Bortecine comprises Bortezomib, which is used in the treatment of Multiple Myeloma and Mantle Cell Lymphoma. This medication is given as an injection. It is advisable to not stop taking this medicine without consulting a medical practitioner. Also, your healthcare provider will decide the dose strength and duration of this medication according to your current medical condition and medical history. Make sure to disclose the details of medicines you already take (including supplements) for better guidance.

Pharmacodynamics

Bortezomib targets the ubiquitin-proteasome pathway which is an essential molecular pathway regulating intracellular concentrations of proteins and promoting protein degradation. The ubiquitin-proteasome pathway is dysregulated in pathological conditions, which leads to aberrant pathway signaling and the formation of malignant cells. The molecular formula of Bortezomib is C19H25BN4O4. Its molecular mass is 384.237 g/mol.

Interactions

All the medicines interact in different manners from person to person. Therefore, it is advisable to consult a healthcare professional to discuss this before the consumption of any new medicine.

Interaction with Alcohol

Interaction with alcohol is unknown. Therefore, be sure to consult your doctor.

Interaction with Medicines 

  • Nitrofurantoin

  • Insulin

  • Infliximab

  • Clozapine

  • Metformin

Disease Interactions

  • Diabetes

  • Hepatotoxicity

  • Cardiac Toxicity

  • Pulmonary toxicity

  • Hypotension

Contraindication 

  • Bortecine 2mg injection is not indicated to the patients having an allergy to Bortezomib or the inactive ingredients of this medicine.

Alternate Brands

The side effects of Bortecine (Bortezomib) injection are mentioned below. It is important to consult a medical practitioner in case these/other side effects occur.

  • Fever

  • Chills

  • Back pain

  • Cough 

  • Constipation

  • Diarrhea

  • Vomiting

  • Blurred vision

  • Bleeding gums

  • Fatigue 

  • Tiredness

  • Weakness

  • Drowsiness

  • Sore throat

  • Skin rash

  • Itching

  • Fainting 

  • Dizziness 

  • Insomnia 

  • Difficulty in breathing

  • Pain or redness on injection site

  • Decreased appetite

  • Peripheral neuropathy (numbness in feet or hands)

  • Neutrophils (decrease in white blood cell count)

  • Anemia (decrease in red blood cell count)

Normal Dose

It is advisable to not self--administer Bortecine (Bortezomib) injection. Your healthcare provider will give you this injection according to your medical condition.

Missed Dose

Initially, it is advisable to not miss a dose. However, if such a case happens, make sure to consult your healthcare provider to schedule an appointment for the same or guide you further.

Overdose

In case you experience symptoms of overdose, immediately call your doctor or any other medical emergency helpline.

 

Pregnancy or Breastfeeding

During Pregnancy or Breastfeeding, Bortecine (Bortezomib) injection is not prescribed for use unless necessary. It is advisable to consult your doctor regarding the potential risks and benefits of this injection.

Driving

After taking Bortecine (Bortezomib) injection, side effects like blurred vision or tiredness may occur. Hence, it is advised to avoid any such activity that demands high concentration (including driving and operating heavy machinery).

Heart or Respiratory Disease

Bortecine (Bortezomib) injection should be administered with caution in patients having a known heart or respiratory disease (including diabetes). Prior discussion with the doctor about the risks and benefits is recommended.

Things to Avoid

  • Alcohol

  • Driving

  • Unwashed fruits and vegetables

  • Raw meat

Q1- What is Bortecine (Bortezomib) injection used for?

A- Bortecine (Bortezomib) injection is an anti-cancer medication, prescribed for the treatment of Multiple Myeloma (a Cancer of Bone Marrow) and Mantle Cell Lymphoma.

Q2- What are the side effects of Bortecine (Bortezomib) injection?

A- The side effects of Bortecine injection are fever, nausea, chills, skin rash, itching, vomiting, diarrhea, anemia, etc. Also, other side effects may occur. Therefore, make sure to call your doctor if the condition worsens.

Q3- How can I take this injection?

A- It is advisable to not self--administer Bortecine (Bortezomib) injection. Your healthcare provider will give you this injection according to your medical condition.

Q4- How should I store Bortecine injection?

A- Store Bortecine (Bortezomib) injection at room temperature (10-30°C).

Q5- What is the strength of Bortecine (Bortezomib) injection?

A- Bortecine (Bortezomib) is available in the strength of 2 mg. It is available in the form of an injection, given by a healthcare provider. 

Q6- Is it safe to drive after taking Bortecine injection?

A- It may not be safe to drive after taking Bortecine injection as it may cause side effects such as drowsiness and lack of concentration. 

Q7- Is it safe to take Bortecine injection during pregnancy or breastfeeding?

A- It may not be safe to take Bortecine injection during pregnancy or breastfeeding as this injection may harm the baby. Therefore, make sure to discuss the potential risks and benefits of taking this medicine. 

Q8- What should I avoid while taking Bortecine (Bortezomib) injection?

A- Avoid the following while taking Bortecine (Bortezomib) injection:

  • Raw meat

  • Alcohol 

Q9- How long should I take this injection?

A- Your doctor will decide the dose strength and duration of this medicine. Do not stop taking this medicine unless your healthcare provider tells you. 

Q10- Can I drink alcohol with this medicine?

A- Alcohol may cause harm. However, the interaction of this medicine with alcohol is unknown. Make sure to consult your doctor for the same.

 

Above Content has been reviewed by Professionals