Brand name - Viroclear
Generic name - Sofosbuvir
Type - Allopathic
Manufacturer - Abbott
Salt composition - Sofosbuvir 400mg
Storage - Store at room temperature (10-30°C)
Dosage form - Oral (tablet)
Strength - 400mg
Packaging - Bottle of 28 tablets
Gender - Unisex
Prescription required - Yes
Indication - Chronic hepatitis C virus (HCV) infection
Viroclear (Sofosbuvir) 400mg is an antiviral medicine. This medication is used in the treatment of chronic (long-lasting) Hepatitis C Virus infection, along with other medications. Viroclear works to lower the multiplication of viruses (HCV) in the body.
Sofosbuvir inhibits the Hepatitis C NS5B protein. Sofosbuvir has a high barrier to the development of resistance. Sofosbuvir is a prodrug of the Protide type, where the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203 followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), along with repeated phosphorylation. Dephosphorylation then creates the inactive metabolite GS-331077. The half life of Sofosbuvir is 0.4 hours, and the half life of GS-331077 is 27 hours. Following a single 400 mg oral dose of sofosbuvir, 80% is normally excreted in urine, 14% in feces, and 2.5% in expired air recovery.
The active ingredient of Viroclear is Sofosbuvir 400mg.
Usage of medicine
Viroclear tablet (400mg) is used to treat chronic Hepatitis C Virus infection in adults. It works to lower the multiplication of HCV in the body.
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Q1- What is Viroclear?
A- Viroclear 400mg tablets are used with other medications to treat chronic (long-lasting) Hepatitis C Virus infection in adults.
Q2- In what strength is it available?
A- Viroclear (Sofosbuvir) is available in the strength of 400mg.
Q3- What are the storage conditions for Viroclear tablets?
A- Store at room temperature (10-30°C). Keep it away from children, direct light and moisture.
Q4- What are the possible side effects of Viroclear 400mg?
A- Viroclear can cause side effects such as fever, chills, insomnia, anemia, diarrhea, loss of appetite, nausea and fatigue. Make sure to consult your healthcare provider if you experience these or any other side effects.
Q5- Can I drive after taking this medicine?
A- If you feel unwell (dizzy or tired) after taking Viroclear tablet, do not drive.
Q6- Is it safe to take Viroclear tablets during pregnancy?
A- Please contact your healthcare provider.
Q7- Is it safe to take Viroclear tablets during breastfeeding?
A- Viroclear 400mg tablet is safe during breastfeeding, only if prescribed by a professional doctor.
Q8- Can I take this medicine in kidney disease?
A- Viroclear should be administered with caution in patients with kidney disease. Make sure to ask your healthcare provider before consuming this medicine.
Q9- How should I take this medicine?
A- Take this medicine with food, at the same time everyday preferably. Ask your healthcare provider about the dose strength.
Q10- Can I take Viroclear (Sofosbuvir) 400mg in liver disease?
A- Consult your healthcare provider before taking Viroclear.
Q11- Is Viroclear a habit forming medicine?
A- No, it is not a habit forming medication.
Q12- What should be done in case of overdose?
A- Seek emergency medical support in case of overdose.
Q13- What if I miss a dose?
A- Take the dose as soon as you remember. However, if it is already the time for the next dose, skip the previous dose and take the next scheduled dose. Do not double the dose strength to catch up.
Q14- Is it safe to operate machinery after taking Viroclear tablet?
A- If you feel unwell after taking this medicine, avoid driving or operating heavy machinery.
Q15- What should I avoid while taking this medicine?
A- Avoid eating sugary foods.
Q16- Is consumption of alcohol safe with this medicine?
A- Avoid consumption of alcohol with this medication.