TEEFAVIR

Mfd. by :- ArecharĀ  Healthcare (Fulfilled By : Magicine Pharma)

Teefavir

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Teefavir   

Generic Name: Tenofovir disoproxil fumarate + Emtricitabine + Efavirenz 

Manufacturer: Arechar  

Dosage Form: Tablet  

Strength: 300mg/200mg/600mg 

Composition: Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg) + Efavirenz (600mg) 

Indication: HIV 

Packaging: 30 tablet  

Storage: Store at room temperature 

Overview  

Tenofovir disoproxil fumarate, Emtricitabine, and Efavirenz are active ingredients that are to prevent the multiplication of HIV (human immunodeficiency virus), and together they form a tablet known as Teefavir and these ingredients work in a combination to decrease the amount of HIV infection. This medication boosts your immune system to fight against HIV and manage AIDS (Acquired immunodeficiency syndrome). Do not stop the dosage of Teefavir tablets without taking permission from your physician.  

Pharmacodynamics  

Tenofovir Disoproxil Fumarate (Teefavir):- This is particularly a nucleoside (acyclic) phosphonate diester analog of adenosine monophosphate. It usually requires initial diester hydrolysis in order to convert it to tenofovir and subsequent phosphorylations through cellular enzymes and form tenofovir diphosphate. It works to inhibit the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination.   

Emtricitabine (Teefavir):- It is a synthetic nucleoside analog of cytidine. This compound is phosphorylated by cellular enzymes for the formation of emtricitabine 5'-triphosphate. Emtricitabine works to inhibit the activity of the HIV-1 reverse transcriptase (RT) through competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporating it into nascent viral DNA resulting in chain termination. The compound is a weak inhibitor of mammalian DNA polymerase alpha, beta, epsilon, and mitochondrial DNA polymerase gamma.  

Efavirenz (Teefavir):- It is an oral non-nucleoside reverse transcriptase inhibitor. This compound is a synthetic purine derivative. It is similar to zidovudine stavudine. It was originally approved to treat HIV infections and AIDS in patients who failed therapy with zidovudine.  

Usage 

Teefavir (Tenofovir disoproxil fumarate + Emtricitabine + Efavirenz) is an anti-HIV tablet, which is used for the treatment of HIV infection and to stop the infection from multiplying. It is advisable to take this medicine as prescribed by your medical practitioner and do not skip your regular dosing schedule. It is necessary to inform your doctor if you have a history of cardiac disease or liver disease. The recommended dose of Teefavir tablet is decided by your healthcare professional. Dosage may vary differently to the patients according to their age, weight, and other health concerns.  

Interactions  

Teefavir tablets may interact with other medicines, diseases, and other elements. It is important to know the same before starting the course of this medicine.  

Medicine Interactions 

  • Gentamicin  

  • Methotrexate  

  • Lamivudine  

  • Ciprofloxacin  

  • Fluconazole 

  • Cisplatin  

  • Tobramycin 

Disease Interactions  

  • Hepatic impairment  

  • CNS orders  

  • Renal dysfunction  

  • Increase in cholesterol levels  

Alcohol Interaction 

Teefavir may or may not interact with alcohol. Please consult a qualified doctor before consuming alcohol.  

Contraindication 

  • This medication is not recommended for use in patients suffering from kidney impairment. 

  • Do not administer Teefavir tablets if you have an allergy to Tenofovir disoproxil fumarate, Emtricitabine, and Efavirenz. 

  • Teefavir tablets are not indicated for use in patients suffering from hypersensitivity.  

Side effects  

Teefavir (Tenofovir disoproxil fumarate + Emtricitabine + Efavirenz) tablets may cause certain side effects. Make sure to inform a qualified healthcare professional about the same and know the ways to manage them. 

Common side effects  

  • Dizziness 

  • Unusual sweating 

  • Skin rash 

  • Itching 

  • Indigestion  

  • Constipation 

  • Redness of skin 

  • Headache 

  • Taste change 

  • Blurred vision 

  • Confusion 

  • Weight loss 

  • Sweating 

  • Mood changes  

  • Nausea 

  • Fever 

  • Chills 

  • Peripheral neuropathy 

  • Stomach ache 

  • Diarrhea 

  • Blood in urine 

  • Irregular heartbeat 

  • Abnormal dream  

  • Confusion  

Note - consult your pharmacist or healthcare professional if any possible side effects occur.  

Dosage 

Take the Teefavir tablets exactly as prescribed by a qualified doctor. Do not crush or chew the tablet. Be sure to avoid skipping a dose.  

Missed dose  

If you miss a dose, consult a medical practitioner. Do not increase the strength of the next dose to cope.  

Overdose 

In case of overdose, be sure to consult a healthcare professional or a medical helpline for proper monitoring.   

Warnings 

General warnings 

  • Tell your healthcare professional about the medicines you take before consuming Teefavir tablets.  

  • If you are suffering from liver or/and kidney disease, avoid the consumption of Teefavir tablets, until your healthcare provider prescribes.  

  • Do not administer this medication without a prescription. 

Warnings for female  

Pregnancy  

  • During pregnancy, Teefavir tablets may cause harm to the developing baby.  

Breastfeeding  

  • During breastfeeding, Teefavir tablets may cause harm to the developing baby.  

Precautions 

  • Teefavir tablet should be used with caution in some patients because it may increase the risk of CNS side effects like drowsiness, hallucinations, etc. 

  • Know about the risks and benefits of taking Teefavir tablets before their consumption.  

  • If side effects last longer than usual, inform your doctor about the same and know the ways to manage them.  

  • Use proper contraceptive measures in order to avoid pregnancy during the course of this medicine.  

Cautions  

  • Do not crush the Teefavir tablets.  

  • Avoid missing a dose.  

  • Do not increase or decrease the dose strength as per your own wish.  

  • Avoid smoking and alcohol consumption during treatment with this medicine.  

Above Content has been reviewed by Professionals