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Glivec 400mg tablet

4.8
Google Rating

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novartis

Pack of

10 tablet Per Strip

Salt Composition

Imatinib

Storage

Keep in cold place

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Glivec 400mg tablet

Glivec 400mg tablet

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Overview

Glivec 400 mg tablet is a medicine is used in the treatment of some forms of cancer. It is prescribed by doctors to treat blood cancers such as chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) and gastrointestinal stromal tumors (GIST). It acts by inhibiting special proteins (also referred to as tyrosine kinases) that assist cancer cells to multiply and grow. Glivec prevents the increase or even the progression of cancer cells by blocking signals. In addition to blood cancers and GIST, Glivec is employed to treat certain rare diseases like dermatofibrosarcoma protuberans (skin tumor) and aggressive systemic mastocytosis (a bone marrow disease).

Indication

  • Chronic Myeloid Leukemia (CML)
  • Acute Lymphocytic Leukemia (ALL)
  • Gastrointestinal Stromal Tumors (GIST)
  • Myelodysplastic/Myeloproliferative Diseases (MDS/MPD)
  • Hypereosinophilic Syndrome (HES)/Chronic Eosinophilic Leukaemia (CEL)
  • Dermatofibrosarcoma Protuberans (DFSP)

Uses of Glivec tablet

  • Chronic Myeloid Leukemia (CML)
  • Acute Lymphocytic Leukemia (ALL)
  • Gastrointestinal Stromal Tumors (GIST)
  • Myelodysplastic/Myeloproliferative Diseases (MDS/MPD)
  • Hypereosinophilic Syndrome (HES)/Chronic Eosinophilic Leukaemia (CEL)
  • Dermatofibrosarcoma Protuberans (DFSP)

Side Effects

This medicine can make your skin more sensitive to sunlight than usual. Sun exposure may lead to rashes, itching, redness, or even severe sunburn. To protect yourself outdoors, wear suitable clothing and apply sunscreen with an SPF of at least 15. If you notice a burning sensation on your skin, inform your doctor. The human body reacts differently to the Glivec 400mg tablet. Responses or undesired symptoms vary from individual to individual. Usually, they disappear with time as the body adjusts to the medicine; these side effects don't need special medical attention. Whereas if the symptoms don't disappear with time or you have severe side effects, then consult your doctor immediately. Some of the common side effects of the Glivec 400mg tablet are mentioned below:

  • Diarrhea
  • Vomiting
  • Nausea
  • Loss of appetite
  • Dizziness
  • Extreme fatigue 
  • Blurred vision
  • Irregular heart rate
  • Chest pain
  • Muscle cramps
  • Pink eye 
  • Redness and rashes, Swelling of joints
  • Trouble sleeping
  • Hair loss
  • Shortness of breath
  • Yellowing of eyes and skin
  • Pink mucous in the cough
  • Sudden weight loss or weight gain
  • Peripheral edema

How To Use

  • Take the dose of the Glivec 400mg tablet as per your healthcare provider’s prescription.
  • Do not stop taking the medicine suddenly, unless your doctor tells you.
  • This medicine is given under the strict supervision of a doctor. Do not self-administer.
  • Overdose is a very unusual state for this medicine because it is given under the supervision of a healthcare provider.
  • Glivec 400mg tablet can be taken without food or with food.
  • The doctor will provide emergency medical treatment.
  • You should not break, crush, or chew the medicine; it should be swallowed as a whole.


How It Works


The Glivec 400mg tablet is an anticancer medicine that acts as a tyrosine kinase inhibitor. Its mechanism of action involves selective inhibition of the protein kinase enzyme known as BCR-ABL, which promotes aberrant growth of cancerous cells. The inhibition of the enzyme ensures the prevention of the multiplication of tumor cells, as well as the induction of apoptosis in cells with the positive BCR-ABL enzyme. Apart from the BCR-ABL enzyme, the drug inhibits other enzymes such as c-KIT and PDGFR.

Safety Advice

Alcohol

UNSAFE

The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking the Glivec 400mg tablet. Consult your doctor for further information.

Pregnancy

CONSULT YOUR DOCTOR

Glivec 400mg tablet may be considered unsafe during pregnancy. Please consult your doctor in such a condition. According to some research data, taking the Glivec 400mg tablet during pregnancy has shown harmful effects on the developing baby.

Breast Feeding

CONSULT YOUR DOCTOR

Glivec 400mg tablet is probably not safe if you're breastfeeding. Kindly consult your doctor before taking the Glivec 400mg tablet while breastfeeding, as there is a chance that it may pass to the developing baby through the breast milk of the mother.

Driving

DANGER

It is advisable not to drive or operate heavy machinery after taking the Glivec 400mg tablet, as you may feel dizzy.

Kidney

CAUTION

Share your medical history with your healthcare expert in case of kidney disease before taking the Glivec 400mg tablet. Patients with renal impairment must be careful while taking the Glivec 400mg tablet. They may require adjustment in the dose.

Liver

CAUTION

Inform your doctor before starting the Glivec 400mg tablet if you have liver disease to avoid any serious side effects. Patients with hepatic impairment must be careful while taking the Glivec 400mg tablet. They may require adjustment in the dose.

Missed Doses

​It is advisable to avoid missing any doses. In case you miss a dose of Glivec tablets, consult your doctor immediately.​

FAQs

What is Glivec 400mg tablet used for?

​Glivec is an anticancer tablet that is primarily used in the treatment of blood cancer.​

How can I take Glivec 400mg tablet ?

​Glivec tablets are taken orally once or twice every day as advised by the doctor.​

How long is the treatment with Glivec 400mg tablet ?

​The doctor decides for how long the treatment with Glivec will continue depending on the condition, stage, and health of the patient.​

Can I drive after consuming Glivec?

​It is advisable to avoid driving and operating heavy machinery as Glivec 400mg causes dizziness as one of the side effects.​

Is it safe to take Glivec during pregnancy?

​Glivec can cause harm to the fetus hence it is advisable to avoid the pregnancy or consult the doctor for the same.​

Does taking a Glivec 400mg tablet affect memory?

Memory impairments have been reported in a few patients. Consult your doctor if you face problems with concentration, loss of memory, or are confused.

At what time should you take the Glivec 400mg tablet for its maximum benefit?

Time and dose are decided by your doctor. A Glivec 400mg tablet should be taken at the same time, usually with a meal and a large glass of water to avoid stomach problems.

Can the Glivec 400mg tablet be given to children?

Consult your pediatrician before using this medicine in young patients. Even though it can be prescribed for certain conditions in children as young as one year old, special precautions are still necessary.

Can Glivec 400mg tablet be given to kidney patients?

No, it is advised to avoid taking the Glivec 400mg tablet if you have serious kidney problems. Consult the doctor before taking this medication.

If you take too many Glivec 400mg tablets by mistake, what should you do?

If you take extra doses of the Glivec 400mg tablet, then you should immediately go to the hospital emergency room or call your healthcare provider right away.

Trusted Medicines, Delivered Worldwide

At our pharmacy, your health is our top priority. All of our medicines are safe, effective, and approved by leading health authorities. We partner exclusively with reliable and reputable manufacturers, ensuring the highest quality standards in every product we deliver.

Enjoy the convenience of fast home delivery, secure packaging, and affordable prices—plus special discounts on bulk orders. We’re proud to offer international shipping to a wide range of countries across Asia, Europe, Africa, the Americas, and beyond, making trusted healthcare accessible no matter where you are.

Whether you're a patient or a healthcare provider, you can order with confidence and compassion. Our goal is to ensure that quality healthcare reaches everyone, everywhere.


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References

Peng B, Dutreix C, Mehring G, Hayes MJ, Ben-Am M, Seiberling M, Pokorny R, Capdeville R, Lloyd P. (2024). Absolute bioavailability of imatinib (Glivec) orally versus intravenous infusion. J Clin Pharmacol. 44(2):158-62 - https://pubmed.ncbi.nlm.nih.gov/14747424/

Zhu J, Yang Y, Zhou L, Jiang M, Hou M. (2024). A long-term follow-up of the imatinib mesylate treatment for the patients with recurrent gastrointestinal stromal tumor (GIST): the liver metastasis and the outcome. BMC Cancer. 10:199 - https://pubmed.ncbi.nlm.nih.gov/20465813/

Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, Kawano K, Hanada M, Kurata A, Takeda M, Muhammad Tunio G, Matsuzawa Y, Kanakura Y, Shinomura Y, Kitamura Y. (2025). Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science. 279(5350):577–580 - https://www.scirp.org/reference/referencespapers?referenceid=2656333

Corless CL, McGreevey L, Haley A, Town A, Heinrich MC. (2024). KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size. Am J Pathol. 160(5):1567–1572. - https://pubmed.ncbi.nlm.nih.gov/12000708/

Mudan SS, Conlon KC, Woodruff JM, Lewis JJ, Brennan MF. (2025). Salvage surgery for patients with recurrent gastrointestinal sarcoma: prognostic factors to guide patient selection. Cancer. 88(1):66–74. - https://pubmed.ncbi.nlm.nih.gov/10618607/

Demetri GD, von Mehren M, Blanke CD, Abbeele AD Van den, Eisenberg B, Roberts PJ, Heinrich MC, Tuveson DA, Singer S, Janicek M, Fletcher JA, Silverman SG, Silberman SL, Capdeville R, Kiese B, Peng B, Dimitrijevic S, Druker BJ, Corless C, Fletcher CD, Joensuu H. (2024). Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med. 347(7):472–480.

Ratings And Reviews

4.8
Google Rating

4.75/5

4 Ratings

5

75.00%

4

25.00%

3

0.00%

2

0.00%

1

0.00%

Riya Pandey

Exceeded my expectations

Excellent quality! I've tried several similar products but Glivec 400mg tablet stands out. The quality is consistent and it's been working great. Packaging was secure and delivery was fast. Definitely worth buying.

a year ago

Matthew M.

Worth every penny

Highly satisfied! Glivec 400mg tablet is a quality product that works as described. Fast delivery and good packaging. Will definitely purchase again from this trusted seller.

10 months ago

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MARKETER DETAILS

novartis

DISCLAIMER

The contents of this website are for informative purposes only. They are not deliberated to be an alternative to any professional medical prescription and treatment. Seek the advice of a qualified health provider for questions regarding the medical condition. Do not ignore any professional medical advice because of something you have read on this website. This website offers links to other websites, thereby enabling you to go to the other website directly. Therefore, Magicine Pharma isn't responsible for the content of the links in the website or links in the linked websites. The links are provided to assist the visitors and are not approved by any professional health provider.